There’s no shame in contemplating how we managed to get around before GPS came to our phones. Some may argue that there is an overreliance on automation since maps have been a proven method of exploration and travel for centuries. Yet, access to technology like GPS has democratized travel and opened the door for society to explore our surroundings in ways few ever thought possible.

For decades, scientists have been clamoring for this type of spatial awareness change, especially as it pertains to cellular environments. Traditional imaging studies have been used to understand the microenvironment in biopsy samples, but many of the techniques employed provide a limited dynamic range, rigorous to set-up, and time-consuming to analyze. Though, a greater understanding of the tissue microenvironment could not only advance disease diagnosis but also has the potential to improve drug therapies and patient outcomes.

In this podcast, sponsored by Nanostring Technologies, we chat with Dr. David Rimm from Yale University School of Medicine about the importance of spatial information in his research and others. Moreover, we discussed how new technology, like Nanostring’s GeoMx™ Digital Spatial Profiler, has allowed him to view tissue samples like never before and what the impact of this type of instrument will have for future research. Take a listen!




David Rimm, MD, PhD

Professor of Pathology and Medicine

Director of Pathology Tissue Services

Director of Translational Pathology

Yale University School of Medicine


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