Panelists:
Thibaut Ben Chimol
Assistant Engineer, Sartorius Polyplus
Panelist
Thibaut Ben Chimol
Thibaut Ben Chimol is an Assistant Engineer at Sartorius Polyplus, bringing over a decade of expertise in evaluating and characterizing transfection reagents, including polymer-based and lipid-based particles, for various types of nucleic acids. Since the COVID pandemic, he has specialized in the generation and characterization of LNPs, focusing on their in vitro evaluation to advance targeted delivery systems.
Kevin Lance, PhD
Director of Product Management
Unchained Labs
Panelist
Kevin Lance, PhD
Kevin Lance, PhD, is the Director of Product Management at Unchained Labs. His expertise covers biophysical characterization of LNPs, proteins, nucleic acids, and viral vectors. Prior to Unchained Labs, his research experience covered the fields of sustained antibody delivery and nanotechnology. He earned his PhD in Bioengineering from the joint UC Berkeley–UCSF Bioengineering Graduate Program.
- Time:
In the rapidly evolving field of lipid nanoparticle (LNP) research, the integration of advanced technologies is crucial for the efficient generation, screening, and characterization of formulations.
In this GEN webinar, our expert speakers will explore a connected workflow of innovative methodologies employed to develop and screen LNP formulations using the Sunscreen high-throughput screening (HTS) equipment from Unchained Labs, in conjunction with the LipidBrick® library from Sartorius Polyplus, a novel range of proprietary cationic lipids. Attendees will gain insights into the characterization of LNPs utilizing the new Stunner AF (Add Fluorescence) from Unchained Labs, which facilitates high-throughput and precise analysis of particle size and encapsulation efficiency. Furthermore, the webinar will delve into the in vitro screening of LNP functionality using the Incucyte® Live-Cell Imaging System from Sartorius. This technology enables comprehensive screening of the transfection efficiency of different LNP formulations across various cell lines and immune cells, paving the way for the optimization of specific formulations tailored to particular cell types and primary T cells. Join us to discover how these advanced tools and methodologies are revolutionizing LNP research and formulation development.
Key learnings include:
- Streamlined LNP workflow using connected tools for formulation, screening, and analysis
- Rapid LNP screening with Sunscreen HTS and LipidBrick® cationic lipid library
- Precise characterization of particle size and encapsulation using Stunner AF
- Functional screening of LNP transfection using Incucyte® live-cell imaging
- Optimized LNP formulations tailored for specific cell types, including primary T cells
A live Q&A session will follow the presentation, offering you a chance to pose questions to our expert panelists.
Produced with support from:
The post Juice up LNP Formulation, Screening, & Analysis with Supercharged Tools appeared first on GEN – Genetic Engineering and Biotechnology News.
