New SMArT platform improves safety of CRISPR gene editing

A team of researchers led by Luigi Naldini at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) has developed a new strategy to significantly improve the precision and safety of CRISPR-Cas9 gene editing...

Building a better biosensor polymer

Credit: © 2021 KAUST; Xavier Pita A new organic (carbon-based) semiconducting material has been developed that outperforms existing options for building the next generation of biosensors. An...

Cholesterol Drug May Weaken Ovarian Cancer’s Metastatic Defense

The accumulation of fluid in the belly, known as ascites, is something that women with advanced ovarian cancer may know all too well. The results of research by a team at Duke University School...

CRISPR-edited fungus boosts protein production and cuts environmental impact

In a new study publishing November 19 in the Cell Press journal Trends in Biotechnology, researchers used a gene-editing technology called CRISPR to increase a fungus's production efficiency and cut its production-related environmental impact...

New funding advances AI-powered technology to track therapeutic and diseased cells

Targeting and treating diseases first requires being able to find specific cells-which is challenging because they travel within the body and can "hide."  Now, a new round of funding will support advancing technology invented at...

Intestinal Stretch Tells Brain to Switch Off Appetite

When we say we feel “full” after eating a meal, we probably think that the feeling of satiety results from having a full stomach. The results of studies by researchers at the University of...

Cell Publishes Breakthrough Research Results of IASO Bio’s Anti-BCMA CAR-T Equecabtagene Autoleucel in Autoimmune...

SHANGHAI, NANJING, China and PLEASANTON, Calif., Oct. 16, 2025 /PRNewswire/ -- IASO Biotherapeutics ("IASO Bio"), a biopharmaceutical company focused on the discovery, development, manufacturing, and commercialization of innovative cell therapies, today announced that the Cell...

Jura Bio’s AI Data Loop Enables Large-Scale De Novo Antibody Design

“High quality, large-scale, fit-for-purpose datasets” continues to be the tagline for artificial intelligence (AI) models aiming to achieve scalable drug discovery to novel targets. While troves of public datasets from the Protein Data Bank...

FDA Grants Regenerative Medicine Advanced Therapy Designation to Gene Therapy for Osteoarthritis

The FDA awarded Regenerative Medicine Advanced Therapy (RMAT) designation to GNSC-001, a potential gene therapy from Genascence that blocks interleukin 1 (IL-1) for the treatment of knee osteoarthritis (OA). The product, which received FDA...

Novel class of encrypted peptides offers hope against drug-resistant bacteria

In a significant advance against the growing threat of antibiotic-resistant bacteria, researchers have identified a novel class of antimicrobial agents known as encrypted peptides, which may expand the immune system's arsenal of tools to...