DNA-based barcoding reveals which nanoparticles successfully deliver genetic therapies
Drug delivery researchers have vastly improved the potential of genetic therapies by overcoming the challenge of consistently getting genes and gene-editing tools where they need to be within cells. Findings of the study spearheaded...
$270M RNA Drug Spinout Targets Rare Genetic Cardiomyopathies
Avidity Biosciences found an eager buyer for its neuroscience pipeline when Novartis shelled out approximately $12 billion to acquire the RNA drug developer, in a deal completed late last month.
But when it came to...
Resident Macrophages Play a Role in Maintaining Murine Intraocular Pressure
When the eye’s drainage system clogs, intraocular pressure (IOP) builds up and causes damage. The pressure can lead to glaucoma and vision loss. Researchers headed by a team at Duke University School of Medicine...
New collaboration aims to accelerate biomedical innovation and education
The Terasaki Institute for Biomedical Innovation (TIBI) and Keck Graduate Institute (KGI) have announced a new collaborative research partnership designed to accelerate biomedical innovation through joint research programs, faculty collaboration, and expanded student training...
Cytotrait secures £3 M seed funding to address global food security and sustainable agriculture
Cytotrait, a biotechnology spinout company from The University of Manchester focussed on the development of novel traits for food and agriculture, today announced the close of its £3 M seed funding round. The investment...
StockWatch: Under Fire from FDA, uniQure Stock Roller-Coasters
uniQure (NASDAQ: QURE) shares finished the regular trading week down only 9% despite the FDA’s hard-line stance and public criticism against the company’s Huntington’s disease (HD) gene therapy candidate AMT-130.
But the agency’s broadsides against...
New optovolution technique uses light to guide protein evolution
Evolution is biology's powerful method of engineering. It works by generating many variants of DNA, RNA, and proteins inside cells and letting nature "select" the organism that performs best. Early farmers started taking advantage...
Engineered lettuce may turn injectable GLP-1 therapies into oral pills
Few drugs have entered mainstream awareness as quickly or as dramatically as glucagon-like peptide-1, or GLP-1 receptor agonists. Initially approved by the FDA for the treatment of type 2 diabetes, they have since also...
From Discovery to Lot Release: A Validated Suite of Assays for Biologics Drug Development
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Potency assays that fail during tech transfer or comparability studies don’t just delay timelines—they erode regulatory confidence and cost development cycles. Advancing drug candidates and maintaining product quality post-approval...
Machine learning detects early brain changes linked to Alzheimer’s disease
Worcester Polytechnic Institute (WPI) researchers have used a form of artificial intelligence (AI) to analyze anatomical changes in the brain and predict Alzheimer's disease with nearly 93% accuracy. Their research, published in the journal Neuroscience,...
