PacBio to commence first customer shipments of Revio long-read sequencing systems

PacBio, a leading developer of high-quality, highly accurate sequencing solutions, today announced its first customer shipments of Revio long-read sequencing systems will commence on March 8, 2023. As previously announced, the Revio system features...

Engineered E. coli shows promise in cancer immunotherapy

Study title: Nonpathogenic E. coli displaying decoy-resistant IL18 demonstrate potent anti-tumor responses and boost CAR-NK cell therapy Publication: Nature Biotechnology Dana-Farber Cancer Institute authors: Rizwan Romee, MD, Shaobo Yang, Michal Sheffer, PhD, David Barbie, MD, Catherine Wu, MD, Robert J. Soiffer, MD, Jerome Ritz, MD

Heightened Genetic Disease Risk Linked to Remote Regions in the U.K.

Individuals from isolated parts of the U.K. could have variations in their genetic code that increase their chance of developing certain diseases, according to a new study “Regionally enriched rare deleterious exonic variants in...

Depleting SIRPα-deficient in macrophages activate tumor antigen-specific cytotoxic T cells

In a study that will be published in Nature Communications on May 28, 2021, a research team led by Dr. Yuan Liu from Georgia State University reports that intratumoral SIRPα-deficient macrophages activate tumor antigen-specific...

New tool can help researchers to better understand the metabolism of microorganisms

Researchers from University of California San Diego, as part of a large collaboration with scientists around the world, have developed a new search tool to help researchers better understand the metabolism of microorganisms. Microbes...

Geraniol alleviates cognitive decline in D-galactose-induced aging mice

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 6, entitled, "Geraniol attenuates oxidative stress and neuroinflammation-mediated cognitive impairment...

Viral host jumps: Humans to animals transmission more common than previously thought

In a recent study published in Nature Ecology & Evolution, researchers harnessed publicly available viral genomic data, using a comprehensive suite of network and phylogenetic analyses to investigate the evolutionary mechanisms underpinning recent viral...

UofL researchers are unmasking an old foe’s tricks to thwart new diseases

When the body encounters bacteria, viruses or harmful substances, its innate immune cells, neutrophils, assemble at the site to combat the invader. Credit: UofL photo. When the body encounters bacteria, viruses or harmful substances, its innate...

When bad cells go good: Harnessing cellular cannibalism for cancer treatment

(Santa Barbara, Calif.) — Scientists have solved a cellular murder mystery nearly 25 years after the case went cold. Following a trail of evidence from fruit flies to mice to humans revealed that cannibalistic...

New blood test could detect ovarian cancer early, improve treatment

High-grade serous ovarian carcinoma (HGSOC) is the most common type of ovarian cancer. It is also the most lethal form, in part because clinicians do not have effective ways to screen women for it...