Breakthrough: Sequencing functional antibody proteins directly from human blood
Rapid Novor Inc., the world’s leader in mass spectrometry (MS)-based antibody protein sequencing, announced today that its REpAb® antibody discovery platform was used to successfully sequence a complex mixture of functional antibodies directly from the...
Bombardier vs. assassin: Mimetic interactions via a shared enemy
Animals can defend themselves against their natural enemies in various ways. Well-defended species often share conspicuous body colors with other well-defended or undefended species, forming mimetic interactions. Bombardier beetles eject toxic chemicals at a...
Expertise in cancer treatment could be used to find a cure for endometriosis
Endometriosis: If we utilize all the knowledge we have about cancer, there is reason to hope that effective diagnosis and treatments can be developed to combat the female condition 'everybody' is talking about. "This...
ASCO: HER2-targeted antibody drug conjugate shows strong anti-tumor activity and durable responses across multiple...
In a new study of trastuzumab deruxtecan, a HER2-targeted antibody drug conjugate, researchers observed encouraging responses and long-lasting clinical benefit in several tumor types. These data from an interim analysis of the Phase II...
Phase 3 SWOG Cancer Research Network trial, led by a City of Hope researcher,...
LOS ANGELES and PORTLAND, Ore. — A Phase 3 trial has demonstrated that patients with advanced stage (3 or 4) classic Hodgkin lymphoma who underwent initial treatment with nivolumab, a PD-1 checkpoint inhibitor, and AVD chemotherapy (N-AVD) had...
Lupus Therapeutics announces three Phase 3 clinical trials testing new therapies for SLE and...
Lupus Therapeutics announced the start of a collaboration to conduct three Phase 3 clinical trials testing an investigational therapeutic ianalumab for systemic lupus erythematosus and lupus nephritis. Lupus Therapeutics, the clinical research affiliate of...
ASCO: Targeted therapy induces responses in HER2-amplified biliary tract cancer
ABSTRACT: 4008
Credit: MD Anderson Cancer Center
ABSTRACT: 4008
CHICAGO ― HER2-targeted bispecific antibody zanidatamab demonstrated durable responses in patients with treatment-refractory HER2-positive biliary tract cancer (BTC), researchers from The University of Texas MD Anderson Cancer Center...
Study shows humans may have evolved a spring-like arch to help us walk on...
During human evolution, the foot underwent strong selective pressures. The pronounced medial arch of the human foot is considered a unique feature in the evolution of habitual bipedalism. A high medial arch in fossil...
Developing technologies to reduce the cost of green hydrogen production
Green hydrogen, which produces hydrogen without the use of fossil fuels or the emission of carbon dioxide, has become increasingly important in recent years as part of efforts to realize a decarbonized economy. However,...
DNA damage repaired by antioxidant enzymes
In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.
Credit: Sara Sdelci / CRG
In crisis, the nucleus calls antioxidant...
