New standards for evaluating aging biomarkers unveiled

A new paper led by Harvard researchers has zeroed in on biomarkers of aging using omic data from population-based studies. The team, which included aging and longevity expert Alex Zhavoronkov, PhD, founder and CEO...

Gene Therapy in Mice Holds Promise for ALS and Dementia

Neuroresearchers at Macquarie University in Australia say they have developed a single-dose genetic medicine that has halted the progression of both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) in mice. The team, which...

Towards more efficient catalysts

Researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS), Harvard Department of Chemistry & Chemical Biology, and Utrecht University have reported on a previously elusive way to improve the selectivity of catalytic reactions, adding a new...

With $170M, BioAge Joins Lilly in Oral, Muscle Preserving Obesity Treatment

Kristen Fortney, PhD, BioAge Labs co-founder and CEO Basking in the glow of a collaboration involving Eli Lilly’s diabetes/weight loss blockbuster tirzepatide, BioAge Labs has completed an oversubscribed $170 million Series D financing, the proceeds...

Innovative treatment increases survival of people with malignant mesothelioma, trial shows

An innovative treatment significantly increases the survival of people with malignant mesothelioma, a rare but rapidly fatal type of cancer with few effective treatment options, according to results from a clinical trial led by...

Sickle Cell Salvation: The Victoria Gray Interview

In July 2019, Victoria Gray, a young mother of four from Forest, Mississippi, became the first patient to receive a CRISPR-based therapy for sickle cell disease (SCD) through the exa-cel therapy trial, sponsored by...

Proteins guide electrons to the right place

Cells need energy to function. Researchers at the University of Gothenburg can now explain how energy is guided in the cell by small atomic movements to reach its destination in the protein. Imitating these...

Platform Process Development for Biomanufacturing

A platform approach to bioprocessing uses the same set of protocols and systems found during early phase development. Scientists then transfer the protocols, by either scaling-up or scaling-out, through to cGMP production. Zoltán Kis, PhD,...

Identifying immunotherapy resistance in liver cancer linked to steatotic disease

A research team of Canadian and French scientists, led by INRS professor Maya Saleh, has been investigating immunotherapy resistance in certain patients with hepatocellular carcinoma (HCC) associated with steatotic liver disease. The findings are...

Breakthrough research unveils effects of ionizing radiation on cellular DNA

Recent release of the waste water from Japan's Fukushima nuclear disaster stirred apprehension regarding the health implications of radiation exposure. Classified as a Group 1 carcinogen, ionizing radiation has long been associated with various...