Expanding the toolbox for drug design: New enzymes for tailoring molecules
Simon Schröder has worked out how enzymes can be used to more easily form the desired bond between two nitrogen atoms. The building blocks for new drugs that help fight bacteria that are resistant...
Researchers discover next-gen lipid nanoparticles for muscle-focused mRNA delivery
A team of researchers based at the University of Toronto's (U of T) Leslie Dan Faculty of Pharmacy has discovered a novel ionizable lipid nanoparticle that enables muscle-focused mRNA delivery while minimizing off-target delivery...
Vaccine Manufacturing in Africa Receives Up to $1B in Support
The board of Gavi, the Vaccine Alliance approved the establishment of the African Vaccine Manufacturing Accelerator (AVMA), a financing mechanism that will make up to $1 billion available to support a sustainable vaccine manufacturing industry...
StockWatch: Analysts Weigh Obesity Drug Market Pegged at $100B by 2030
By Alex Philippidis
Is celebrity use, confirmed or otherwise, enough to propel the fast-growing market for obesity drugs into a stratosphere as high as $100 billion by 2030, as projected recently by Barclays, Goldman Sachs,...
FDA Approves Casgevy, the First CRISPR Therapy, for Sickle Cell Disease
By Kevin Davies, PhD
In a truly historic decision today, the U.S. Food and Drug Administration (FDA) has, as expected, approved Casgevy, the groundbreaking CRISPR-based gene editing therapy for sickle cell disease (SCD), sponsored by...
Atlantic Ocean near Bermuda is warmer and more acidic than ever, 40 years of...
Decade-long ocean warming which impacts ocean circulation, a decrease in oxygen levels that contributes to changes in salinification and nutrient supply, and ocean acidification are just some of the challenges the world’s oceans are...
UTA receives $1.1 million grant to train researchers in mathematical and computational methods for...
The National Science Foundation (NSF) has awarded The University of Texas at Arlington a $1.1 million grant to train and mentor three multi-level cohorts of interdisciplinary researchers in mathematical and computational techniques to address...
Allergy Drug Added to Immunotherapy Benefits Lung Cancer Therapy in Small Trial
Researchers at the Icahn School of Medicine at Mount Sinai have identified an allergy pathway that, when blocked, unleashes antitumor immunity in mouse models of non-small cell lung cancer (NSCLC). The team reported data from...
Johnson Matthey Partners with Basecamp Research on Biocatalysis Solutions
Johnson Matthey (JM), a specialty chemicals and sustainable technologies company, reports that it has partnered with Basecamp Research, which maps global biodiversity for computational biodesign applications, to accelerate the adoption of more sustainable, bio-based catalysts.
The partnership...
New drug combo fights breast cancer with brain metastases
A combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended progression-free survival among patients with unresectable locally advanced or metastatic HER2-positive breast cancer, compared with T-DM1 alone, according to results...
