Lock Down the Critical Factors in Oligo and Oligo-Conjugate Characterization with Stunner and Honeybun
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Kevin Lance, PhD Director, Product ManagementUnchained Labs View Bio
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A Method for Assessing Lab-Grown Stem Cell-Derived Embryo Models
University of Sydney researchers have developed a powerful way to test how closely lab-grown biological models resemble real human embryos, finding that while some models perform well, none yet fully capture the complexity of...
Watching Cancer Proteins in Real Time, with Help from Rare Earth Elements
A long-duration single-molecule imaging platform from the Broad Institute and MIT has revealed unexpected stability in homodimers of HER3, one of the most enigmatic members of the ErbB receptor family. The research, published in...
Neurons Involved in Generating Anxiety After Cannabinoid Drug Exposure Identified in Mice
Working with mice, Northwestern scientists have for the first time identified a set of neurons in the brain that play a role in generating anxiety after exposure to cannabinoid drugs, especially under stressful conditions....
Talus Bio’s Structure-Free AI Model Targets Unstructured Proteins in Their Native Cellular Context
Alex Federation, PhD, has been interested in undruggable targets since his days as a trainee in the laboratory of Jay Bradner, MD, then at Dana-Farber Cancer Institute now at Amgen. At the time, the...
Designing Peptide Screens to Generate Knowledge, Not Just Hits
Peptide discovery is entering an era of abundance. Researchers can build larger libraries, incorporate noncanonical residues, constrain backbones in multiple ways, and use increasingly capable computational tools to propose or rank candidates. Yet many...
Genome-Wide Analysis Identifies BACH2 as Potential Fetal Hemoglobin Activation Target
In a major new genome-wide meta-analysis, researchers at Boston Children’s Hospital and the Broad Institute led by Vijay G. Sankaran, MD, PhD, have identified a novel regulatory pathway that activates the expression of fetal...
Current Challenges in CAR T Manufacturing
CAR T therapy has undergone a remarkable transformation over the past decade, evolving from an experimental treatment into a clinically validated therapeutic platform with seven FDA-approved therapies and a rapidly expanding global market estimated...
Scientists Observe Enzymes Breaking Down DNA in Real Time
Researchers at the Nano Life Science Institute at Kanazawa University in Japan say they have directly visualized how enzymes find and break DNA molecules in real time. Using high-speed atomic force microscopy, the team...
Thar Process Partners with ExtrateX to Bring Prep to Process-Scale SFC to Europe
Thar Process, based in Pittsburgh, PA, a specialist in supercritical CO2 extraction and purification technology (SFE and SFC), partnered with ExtrateX, a French expert firm in supercritical fluid systems, to represent and distribute its...
