Go with the flow

The antibiotic cefazolin is an essential drug according to the World Health Organization (WHO). It is usually produced via batch manufacturing, but this multistep process is time-consuming, wasteful and requires very specialized facilities. Now...

Powerful gene editing approach boosts rotifers in pantheon of laboratory animals

By Wynne Parry Credit: Michael Shribak and Kristin Gribble By Wynne Parry Much about tiny, swimming rotifers makes them ideal study subjects. Although barely visible to the naked eye, these transparent animals and their innards are readily...

Morris Animal Foundation-funded researchers establish new reptile cell lines

DENVER/Aug. 4, 2023 – A recent scientific paper published in the journal Microorganisms highlights the development of the first broad range of reptile cell lines, a significant feat that researchers say will help advance...

New method for assessing the structural changes in cardiac arrhythmia

A multidisciplinary study led by scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) presents a new method for assessing the structural and electrophysiological changes, called atrial remodeling, produced in the heart of patients...

Deep learning improves protein design by 10x

The key to understanding proteins -; such as those that govern cancer, COVID-19, and other diseases -; is quite simple. Identify their chemical structure and find which other proteins can bind to them. But...

Researchers strengthen defenses against common cyberattack

RICHLAND, Wash.—Scientists have developed a better way to recognize a common internet attack, improving detection by 90 percent compared to current methods. Credit: Animation by Sara Levine | Pacific Northwest National Laboratory RICHLAND, Wash.—Scientists have developed...

Insilico Medicine’s new AI tool shows promise in predicting clinical trial outcomes

Insilico Medicine ("Insilico"), a clinical-stage end-to-end generative artificial intelligence (AI) drug discovery company, has demonstrated that it can predict the outcome of Phase II to Phase III clinical trial success using its proprietary transformer-based...

Fully electrical proof-of-concept biosensor for detecting RNA cancer biomarker sequences in solution at the...

In a recent study published in Scientific Reports, a group of researchers investigated single-molecule electrical detection of ribonucleic acid (RNA) cancer biomarkers, demonstrating high sensitivity and specificity in distinguishing mutants and paving the way...

Calculations reveal high-resolution view of quarks inside protons

UPTON, NY—A collaboration of nuclear theorists at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory, Argonne National Laboratory, Temple University, Adam Mickiewicz University of Poland, and the University of Bonn, Germany, has used...

Phase 1 clinical trial underway to test City of Hope-developed cancer treatment

Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, today published a new study explaining how they took a protein once thought to be too...