Safety of a gene therapy to treat alpha 1-antitrypsin deficiency

Researchers report on the safety of a gene therapy to treat the common autosomal recessive hereditary disorder alpha 1-antitrypsin (AAT) deficiency in a new article in the peer-reviewed journal Human Gene Therapy. In ATT...

Elementary Claim: Sherlock Gains Patent Rights for Cas12 in Diagnostics

Bryan Dechairo, PhD, Sherlock Biosciences president and CEO Sherlock Biosciences has gained U.S. rights to a patent for diagnostic use of a CRISPR system based on the smaller Cas12 enzyme as single RNA-guided endonuclease. Sherlock—whose co-founders include...

HKUMed identifies novel host protease determinants for SARS-CoV-2 infection

Researchers from Department of Microbiology, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has identified novel host protease determinants, that facilitate the infection of SARS-CoV-2, including the Omicron...

Life Sciences Innovator Category Winner 2023

Following a rigorous application process, we are proud to announce that Seda have been selected as the UK Life Sciences Innovator Winner 2023 in the Application, Product & Service Design Category. The Life Sciences...

Telomeres Encode Disease-Relevant Proteins

University of North Carolina (UNC) researchers Taghreed Al-Turki, PhD, and Jack Griffith, PhD, have made the discovery that the telomeres on the ends of chromosomes contain genetic information that codes for two small proteins, one...

Adipose-targeted delivery of thyroid hormone alleviates hypercholesterolemia and atherosclerosis

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has developed thyroid hormone (TH) - encapsulated nanoparticles modified with adipose-homing peptide, which selectively transport TH to adipose tissues. This...

Newly discovered form of salty ice could exist on surface of extraterrestrial moons

The red streaks crisscrossing the surface of Europa, one of Jupiter’s moons, are striking. Scientists suspect it is a frozen mixture of water and salts, but its chemical signature is mysterious because it matches...

What physicists can learn from shark intestines

ROCKVILLE, MD – In 1920, inventor Nikola Tesla patented a type of pipe that he called a “valvular conduit,” which was built to draw fluid in one direction without any moving parts or added...

How AI can help design drugs to treat opioid addiction

ROCKVILLE, MD – Approximately three million Americans suffer from opioid use disorder, and every year more than 80,000 Americans die from overdoses. Opioid drugs, such as heroin, fentanyl, oxycodone and morphine, activate opioid receptors....

Results of pharmacokinetic analysis show Omomyc mini-protein maintains its structural integrity in tumor tissue...

Results of pharmacokinetic analysis show Omomyc mini-protein maintains its structural integrity in tumor tissue for at least 72 hours following administration Credit: VHIO Results of pharmacokinetic analysis show Omomyc mini-protein maintains its structural integrity in...