Staying the Course: New CEO, Same Focus for Astellas Gene Therapies
The appointment of a new CEO by Astellas Pharma—Japan’s fourth largest pharma company—is unlikely to slow down its development of gene therapies—efforts boosted by the recent lifting of a clinical hold affecting one lead...
NIH scientists develop mouse model to study mpox virulence
WHAT:
Scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have removed a major roadblock to better understanding of mpox (formerly, monkeypox). They developed a mouse...
Functional Phosphoproteomics Finds Resolutions with Ion Mobility
Broadcast Date: March 14, 2023Time: 8:00 am PT, 11:00 am ET, 17:00 CET
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Phosphoproteomics is a cutting-edge research area that aims to understand the role of phosphorylation, a widespread modification of proteins, in...
A tool to prevent deaths due to female underrepresentation in clinical trials
ROCKVILLE, MD – Women are often underrepresented in cardiac clinical trials—yet they are at least at equally high risk of death due to cardiovascular disease, and at higher risk of developing drug-induced heart complications...
Algorithm Profiles Metabolic Gene Clusters in the Human Gut Microbiome
A collaborative study has developed a software called gutSMASH that identifies primary metabolic gene clusters (MGCs) in specific microbial taxonomic groups that are important in host–microbiome interactions. Although built to predict MGCs from anaerobic...
Good news for quality control of messenger RNA (mRNA) medications
Tokyo, Japan – Researchers from Tokyo Metropolitan University and RIKEN CSRS have developed a new analytical platform based on liquid chromatography, mass spectrometry and software analysis that quantifies the structure of messenger RNA (mRNA)...
Computer model IDs roles of individual genes in early embryonic development
Computer software developed at Washington University School of Medicine in St. Louis can predict what happens to complex gene networks when individual genes are missing or dialed up more than usual. Such genetic networks...
Highlights from the journal CHEST®, February 2023
Glenview, Illinois – Published monthly, the journal CHEST® features peer-reviewed, cutting-edge original research in chest medicine: Pulmonary, critical care and sleep medicine and related disciplines. Journal topics include asthma, chest infections, COPD, critical care, diffuse lung disease,...
Bread made from whole cell pulse flour simulates satiety hormones to help us feel...
Bread made from a new type of whole cell pulse flour can lower blood glucose (sugar) levels and keep you fuller for longer, new research has found. A study published recently in The American...
Microexon Gene Fragments in Islet Cells Could Represent New Diabetes Targets
When cells copy DNA to produce RNA transcripts, some stretches of the genetic material are included—these are known as exons—but the rest is thrown out. The resulting transcript is a fully mature RNA molecule,...
