A step towards precision oncology for patients with metastatic urothelial carcinoma

Bonn, December 30, 2022 – Dr. Niklas Klümper, resident at the Clinic for Urology and working group leader at the Institute for Experimental Oncology at the University Hospital Bonn (UKB), was awarded the C....

Study discovers triple immunotherapy combination as possible treatment for pancreatic cancer

HOUSTON ― Researchers at The University of Texas MD Anderson Cancer Center have discovered a novel immunotherapy combination, targeting checkpoints in both T cells and myeloid suppressor cells, that successfully reprogrammed the tumor immune...

Study reveals how chronic blood cancer transitions to aggressive disease

A type of chronic leukemia can simmer for many years. Some patients may need treatment to manage this type of blood cancer — called myeloproliferative neoplasms (MPN) — while others may go through long...

Human Brain Organoids Implanted into Mice Connect to Animals’ Cortex and Respond to External...

A research team says it has shown for the first time that human brain organoids implanted in mice have established functional connectivity to the animals’ cortex and responded to external sensory stimuli. The implanted...

Octopus Intelligence Sheds Light on Evolution of Complex Brains

Meeting an octopus is, in many respects, the closest we can come to meeting interplanetary aliens. Yet, new research shows their brains have some startling commonalities to those of humans—perhaps most notably in terms...

Aging | DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary...

“This is the first report to explore changes over time in several of the latest DNAm biological aging measures ” Credit: 2022 Reed et al. “This is the first report to explore changes over time in...

Nerve Pathway Discovery May Lead to New Therapies for Mental Disorders

Researchers in Japan have identified a nerve pathway in mice involved in the processing of rewarding and distressing stimuli and situations. The pathway, originating in a bundle of brain stem nerve fibers called the median...

Here’s Why PDS Biotechnology (NASDAQ:PDSB) Stock Rose … – TipRanks

PDS Biotechnology (NASDAQ:PDSB) gained about 24% in yesterday’s trading session and hit a new 52-week high of $11.48 mid-day. The positive data from an ongoing National Cancer Institute-led Phase 2 trial of the company’s...

Oncotarget | The role of pyrethroid derivatives in autophagy and apoptosis crosstalk signaling and...

“Pyrethroid derivatives and related products exposure have revealed to intensify various ailments and adverse health consequence in the different age groups ”  Credit: 2022 Puvula et al. “Pyrethroid derivatives and related products exposure have revealed to...

Precision Phenotyping for Obesity Pharmacotherapy

Despite a plethora of interventions, including diet, exercise, and medications, obesity continues to be a significant health problem. The fight against obesity currently involves substantial trial-and-error, out-of-pocket costs, and adverse effects. Obesity medications cause...