Guideline-directed hemoglobin targets in children with kidney disease may not optimize growth

Among 510 children and young adults with chronic kidney disease (CKD) followed for over 15 years, declining hemoglobin levels were associated with significant growth impairment even when hemoglobin levels were above guideline directed targets. Credit:...

Multi-stage HIV vaccine regimen shows promising results in Phase 1 clinical trial

The George Washington University Vaccine Research Unit in partnership with Scripps Research, IAVI, Fred Hutchinson Cancer Center (FHCC) and the National Institutes of Health, National Institute of Allergy and Infectious Diseases Vaccine Research Center...

Antibodies against gentamicin associated with increased risk of type 1 diabetes in children

Antibodies produced against the commonly used antibiotic, gentamicin, appear to increase the risk of type 1 diabetes in children already genetically at risk, scientists say. When Medical College of Georgia scientists compared the blood...

Understanding the vector composition of mRNA filled

insights from industryStefan CairnsProduct Technical Specialist Malvern Panalytical  In this interview, Malvern Panalytical Product Technical Specialist, Dr Stefan Cairns, discusses how size exclusion chromatography coupled with static light scattering (SEC-SLS) and other detectors can help you...

Heart Attacks Mimicked on a Chip

Scientists at the University of Southern California Alfred E. Mann Department of Biomedical Engineering say they have developed a “heart attack on a chip,” a device that could one day serve as a method...

BRIM Biotechnology receives FDA orphan drug designation for treatment of neurotrophic keratitis – Ophthalmology...

BRIM Biotechnology announced this week the FDA granted orphan drug designation to BRM424 (BRIM Biotechnology) to treat neurotrophic keratitis (NK), a rare degenerative eye disease that causes very severe corneal damage and destruction of...

Low-intensity ultrasound therapies may help rebuild stronger knees

Low-intensity ultrasound therapies may one day rebuild stronger knees following injury or surgery, thanks to research by Dr. Anu Subramanian at The University of Alabama in Huntsville (UAH) that's being supported by the National...

T-DXd leads to longer overall survival in HER2-positive metastatic breast cancer patients than T-DM1

Second-line treatment with trastuzumab deruxtecan (T-DXd) led to significantly longer overall survival compared with trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer, according to updated results from the DESTINY-Breast03 phase III clinical...

How behind-the-scenes sound mixing makes movie magic #ASA183

NASHVILLE, Tenn., Dec. 7, 2022 – If you’ve ever watched a movie where the audio is out of sync, it quickly becomes obvious that smooth, consistent sound is critical for movie enjoyment, especially during...

Study reports overall response of HER2-low breast cancer patients to neoadjuvant T-DXd treatment

Patients with localized, hormone receptor-positive, HER2-low breast cancer treated with trastuzumab deruxtecan (T-DXd, Enhertu) in the neoadjuvant setting had an overall response rate of 75 percent in the absence of anastrozole and 63 percent...