Automated production of lung organoids could revolutionize the development of treatments
A team of scientists have developed a simple method for automated manufacturing of lung organoids which could revolutionize the development of treatments for lung disease. These organoids, miniature structures containing the cells that real...
Epigenetic drift explains why the aging intestine becomes more vulnerable to cancer
Researchers from the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena, Germany, the Molecular Biotechnology Centre (MBC) in Turin and the University of Turin, Italy, have discovered a fundamental mechanism of...
Fever-resistant bird flu viruses pose a significant threat to humans
Bird flu viruses are a particular threat to humans because they can replicate at temperatures higher than a typical fever, one of the body's ways of stopping viruses in their tracks, according to new...
UBQLN2 liquid droplets emerge as key catalysts of early α-synuclein aggregation
Parkinson's disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the Lewy bodies (LBs) that accumulate in neurons in the substantia nigra region of the brain, damaging these neurons...
Novel mRNA-based therapy may offer a new path to tackle antibiotic-resistant infections
Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have reported early success with a novel mRNA-based therapy designed to combat antibiotic-resistant bacteria. The findings, published in the November 26 online...
Mapping the Neural Mechanism Behind Social Isolation Following Immune Challenge
“I just can’t make it tonight. You have fun without me.” Across much of the animal kingdom, when infection strikes, social contact shuts down. A study headed by researchers at The Picower Institute for...
Backbone Potential: Actuate’s Elraglusib Shows Promise vs. Pancreatic Cancer
Five years after Alex Trebek shared publicly his diagnosis of stage IV metastatic pancreatic cancer, therapies for the disease remain few, and limited to specific patient subgroups.
Metastatic pancreatic cancer accounts for approximately 80–85% of...
New medication offers potential treatment for patients with deadliest form of blood cancer
Biomedical research that began at the University of Virginia School of Medicine has yielded a much-needed new treatment for patients with the deadliest form of blood cancer. The federal Food and Drug Administration has...
Metformin’s Surprising Potential Benefits in Type 1 Diabetes Therapy
A Garvan Institute of Medical Research-led clinical trial has found that using the type 2 diabetes (T2D) drug metformin reduces insulin needs in type 1 diabetes (T1D), a finding that could potentially point to...
COVID vaccine tech could help prevent muscle damage from snakebites
The same technology used in COVID-19 vaccines could help prevent muscle damage from snakebites, according to a new study published in Trends in Biotechnology today . Scientists from the University of Reading and the Technical University of...
