Top 20 Drugs Heading for the Patent Cliff, 2026-2029
The idea of a “patent cliff” wave of exclusivity expirations shaking up the biopharma industry isn’t new: GEN first mentions the term in 2010 and again a year later when Lipitor (atorvastatin) lost its...
Pioneering technology enables scalable production of human kidney organoids
A research team led by the Institute for Bioengineering of Catalonia (IBEC) and collaborating with the Biomedical Research Institute of A Coruña (INIBIC), as well as other international research groups, has developed pioneering technology...
In a First, Scalable Production of Human Kidney Organoids Using Perfused Pig Kidneys
A pioneering technology has been developed that enables human kidney organoids to be produced in a scalable manner by allowing the organoids to be combined with ex vivo pig kidneys and then transplanted back...
How NEB’s Customized Solutions Team Drives Innovation and Partnership in Biotech
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When developing novel life science products, developers may face challenges in areas such as technical expertise, reagent optimization, manufacturing scale, turnaround time, reagent quality, and comprehensive logistical support. These...
Global Virus Network announces the addition of three new Centers of Excellence
The Global Virus Network (GVN), a coalition of leading medical virologists representing 80+ Centers of Excellence and Affiliates in 40+ countries, today announced the addition of three new Centers of Excellence: the USF Health...
Low-cost biosensor identifies altered protein levels associated with psychiatric disorders
Brazilian researchers have developed a low-cost, portable biosensor that can quickly identify a protein whose altered levels are associated with psychiatric disorders, such as depression, schizophrenia, and bipolar disorder. When it becomes commercially available...
3D-printing soft robot delivers hydrogels to the vocal cord surgical site to reconstruct tissues
After vocal cord surgery, many patients develop stiff vocal folds that impact their ability to speak. Hydrogels can help prevent this by promoting healing, but delivering hydrogels to the vocal cords is difficult. Publishing...
Functionalized Fibrin Gel Spurs In-Gel Production of hiPSCs
Fibrin hydrogel, an oft-used two-dimensional scaffold for in vitro cell culture, was recently functionalized to grow human induced pluripotent stem cells (hiPSCs) in three dimensions. This advance makes it easier and more efficient for...
Scaling Perfusion: How Small-Scale ATF Systems Bridge the Gap to Commercial mAb Manufacturing
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Upstream process intensification using perfusion cell culture has become a necessity for meeting today’s demand in monoclonal antibodies (mAbs) bioprocessing. By sustaining higher viable cell densities, extending culture duration,...
New software enables real-time pathogen surveillance in the air and environment
Metagenomics is the study of all organisms present in a particular environment, such as soil, water, or the human body. A key part of metagenomic analysis is understanding what species are present (classification), how...
