CRISPR-GPT helps scientists to generate designs, analyze data and troubleshoot design flaws
Stanford Medicine researchers have developed an artificial intelligence tool to help scientists better plan gene-editing experiments. The technology, CRISPR-GPT, acts as a gene-editing "copilot" supported by AI to help researchers - even those unfamiliar...
Triple negative breast cancer exploits lymph node niches to block immune defense
In almost all solid tumors - i.e. cancers with a solid tissue structure - the detection of tumor cells in the lymph nodes is considered a decisive marker for the progression of the disease....
Visual Cortex Illusion Circuits Mapped with Two-Photon Holography
Every illusion has a backstage crew. New research shows the brain’s own “puppet strings”—special neurons that quietly tug our perception—help us see edges and shapes that don’t actually exist. When four black “Pac-Man” shapes...
Revitalized Microbial Systems Enable Development and Manufacturing of Innovative Biologics
Introduction
Microbial production systems, such as Escherichia coli and yeast, are becoming more important than ever in manufacturing innovative biologics—including nanobodies, enzymes, cytokines, growth hormones, virus-like particles, and other complex modalities such as protein-drug...
StockWatch: Analysts See Pain, and Necessity, in Novo Nordisk’s 9,000 Layoffs
Novo Nordisk (NASDAQ Copenhagen: NOVO-B) inflicted much pain—and much-needed pain—on the company when president and CEO Maziar (Mike) Doustdar announced plans to lay off about 9,000 of its 78,400 employees, a spot check of...
Unlocking hidden soil microbes for new antibiotics
Most bacteria cannot be cultured in the lab-and that's been bad news for medicine. Many of our frontline antibiotics originated from microbes, yet as antibiotic resistance spreads and drug pipelines run dry, the soil...
Paradigms Shifts in Sequencing
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The compromise between sequencing speed and capacity has impacted research for years. To combat this conundrum, in 2018, MGI launched the high-throughput sequencer, DNBSEQ-T7 that can output 7Tb of...
CDMO Roundup
According to the latest study from BCC Research, the demand for “Global Market Opportunities and Competitive Landscape for CDMOs” was valued at $128.0 billion in 2023 and is expected to grow from $136.6 billion...
QuEChERS method enhances detection of harmful compounds in food
In today's world, people are increasingly prioritizing their health and well-being, with daily exercises and calorie-tracking apps becoming the new norm. People are therefore interested in incorporating highly nutritious food items such as fruits...
Manufacturing Challenges with High-Concentration Biologics
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Recent advances in subcutaneous delivery methods now enable patient self-delivery of monoclonal antibody (mAb) therapies. Subcutaneous therapies often require concentrations around 100 to 200 mg/mL. Key issues faced during...
