Dementia-like protein clumping found in early pancreatic cancer cells
Cancer Research UK-funded scientists have uncovered dementia-like behavior in pancreas cells at risk of turning into cancer. The findings provide clues that could help in the treatment and prevention of pancreatic cancer, a difficult-to-treat...
Made Scientific Opens Its New GMP Manufacturing Facility and HQ in Princeton, NJ
CDMO Made Scientific held the grand opening of its new 60,000ft2 cell therapy GMP manufacturing facility and headquarters in Princeton, NJ.
The opening marks the completion of a $12 million initial investment in facility upgrades,...
Antibacterials May One Day Be Derived from Ancient Archaea
Following the drive to understand and control bacteria, it’s becoming clear that our methods have changed the very organisms we aim to understand, increasing resistance to tried-and-true antimicrobial methods. As antibiotic and antibacterial resistance...
Scaffold-free cellular spheroids generate integrated osteochondral grafts
A new study in the peer-reviewed journal Tissue Engineering, Part A demonstrates the potential to produce cellular spheroids, from a clinically relevant embryonic stem cell derived mesenchymal stem cell (ES-MSC) source, to generate scaffold-free chondrogenic or...
Synthetic Metagenomic Method Uncovers Genetic Drivers of Antimicrobial Resistance
Antimicrobial resistance studies often focus on individual protein variants, neglecting broader protein family dynamics. Dihydrofolate reductase (DHFR), a key antibiotic target, has been extensively studied using deep mutational scanning, yet resistance mechanisms across this...
Study investigates aging-related mechanisms in idiopathic pulmonary fibrosis using AI approaches
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease characterized by the excessive accumulation of extracellular matrix components, leading to a gradual decline in lung function and, ultimately, respiratory failure. Predominantly affecting...
AI breakthrough designs peptide drugs to target previously untreatable proteins
A study published in Nature Biotechnology reveals a powerful new use for artificial intelligence: designing small, drug-like molecules that can stick to and break down harmful proteins in the body - even when scientists...
Breaking the Link Between Alcohol Use and Pancreatic Cancer
Despite increasing evidence linking alcohol consumption to cancer, little is known about the biological mechanisms behind the association. Now, researchers at the University of Miami report that inhibiting a cellular molecule called CREB might thwart...
New method greatly improves the precision of genome editing
A research team headed by the University of Zurich has developed a powerful new method to precisely edit DNA by combining cutting-edge genetic engineering with artificial intelligence. This technique opens the door to more...
How Organoids Are Revolutionizing Neuroscience Research
Panelists:
Angels Almenar-Queralt, PhD Assistant ProfessorUniversity of California, San Diego View Bio
Panelist ...
