Innovative approach for the development of next-generation cancer therapies targeting FGFR2/3
Aberrations in fibroblast growth factor receptors FGFR2/3 are major drivers of many cancers-including intrahepatic cholangiocarcinoma, endometrial, breast, gastric, and bladder cancers. However, the development of selective inhibitors targeted FGFR2/3 has long been challenged by...
New study moves closer to defeating dormant tuberculosis cells
New drugs that target 'zombie' tuberculosis (TB) cells are now a step closer, thanks to a new study led by the University of Surrey, published in Scientific Reports. Many dangerous pathogens, including the bacteria...
How Climate Changes Are Impacting Infectious Diseases
Everywhere you look—on land, in the sky, or under the sea—things are heating up! Scientific studies reveal that Earth’s average temperature has climbed by roughly two degrees Fahrenheit (one degree Celsius) since 1850, with...
Unlocking the Mystery Behind Barrett’s Esophagus
A team led by researchers at Baylor College of Medicine and Washington University School of Medicine has shed light on the process that drives Barrett’s esophagus formation. This condition affects the lining of the...
OxPhos System Evolution Explored, Indicating Links Between Mutations and Disease
Mitochondria are known as the body’s “energy factories,” and their function is essential for life. Inside mitochondria, a set of complexes called the oxidative phosphorylation (OxPhos) system represents the main site of metabolic and...
ProBio Opens Flagship U.S. Plasmid & Viral Vector Manufacturing Facility
ProBio, a CDMO and subsidiary of GenScript Biotech, opened its flagship Cell and Gene Therapy Center of Excellence at the Princeton West Innovation Campus in Hopewell, NJ. The 128,000-sq-ft GMP facility is purpose-built for...
Optibrium partners with TalTech on EU-funded PhD program to advance sustainable drug discovery
Optibrium, a leading developer of software and AI solutions for molecular design, today announced its partnership with TalTech (Tallinn University of Technology) to co-supervise an EU-funded PhD position as part of the INNOCHEMBIO programme....
Experimental medication sensitizes glioblastoma to treatment and blocks tumor spread
A potential treatment for glioblastoma crafted by scientists at The Wertheim UF Scripps Institute renders the deadly brain cancer newly sensitive to both radiation and chemotherapy drugs, and blocks the cancer's ability to invade...
Healx and SCI Ventures Partner to Uncover Cures for Paralysis with AI-Driven Drug Discovery
Healx, an expert in AI-powered drug discovery for rare and neglected conditions, has partnered with SCI Ventures to try to accelerate the discovery and development of therapies for spinal cord injury (SCI) using artificial...
Shift Bioscience proposes improved ranking system for virtual cell models to accelerate gene target...
Shift Bioscience (Shift), a biotechnology company uncovering the biology of cell rejuvenation to develop new therapies for age driven diseases, today announced the results of a new study detailing an improved approach to ranking...
