Illumina Launches New MiSeq i100 Series with XLEAP Chemistry, RT Reagents
Weeks of teasers on social media noting that “Something big is coming. And it’s small,” have sparked a guessing game (and some patent searching) among NGS aficionados. But today, Illumina quelled the rumors with...
AI-designed drug ISM5939 granted IND clearance for cancer clinical trials
Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, announced that it has received IND clearance from FDA for ISM5939, a potential best-in-class oral small molecule inhibitor targeting ENPP1 for the...
Updated Protocols for Managing Blood Cancers During Pregnancy
A groundbreaking set of guidelines has emerged to navigate the complexities of diagnosing and managing serious blood cancers during pregnancy. The prevalence of blood cancers, such as acute leukemia and aggressive lymphomas, although rare,...
Downstream Bottlenecks are Slowing mAbs Manufacturing: This New TFF Tech Can Help
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For decades, therapeutic monoclonal antibody (mAb) production relied on traditional batch-based manufacturing using stainless steel systems. But as biopharmaceutical pipelines grow to meet rising demand for these important biologics,...
New model predicts mRNA protein production, accelerating drug and vaccine discovery
A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently specific mRNA sequences will produce proteins, both generally and in various cell types. The new advance,...
Garvan Institute and Illumina collaborate to transform the treatment of complex diseases
Illumina, a global genomics and human health company, has partnered with the Garvan Institute of Medical Research's TenK10K project to help transform the treatment of complex diseases, starting with autoimmune diseases, with a joint...
Extrachromosomal DNA Carrying MYC Drives Pancreatic Cancer Aggression
Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%. The poor prognosis is due in part both to late detection and the cancer’s capacity to adapt and...
Bridging Technologies Renew Hope for Treating Inflammatory Diseases
Large unmet needs for autoimmune disease therapeutics remain. For many patients, including approximately 25% of those with graft versus host disease (GvHD), existing therapeutics are inadequate. The outlook for better ones, though, is increasingly...
SARS-CoV-2 Likely Spread Through Wildlife Trade, Not Bat Migration
Since the start of the COVID-19 pandemic, there has been controversy surrounding the origins of SARS-CoV-2. New research from the University of California, San Diego (UCSD), School of Medicine suggests that the virus likely...
RNA quality control protein PELOTA found to slow aging and extend lifespan
As aging progresses, the quality of DNA and proteins inside cells declines, known to be the cause of various degenerative diseases. However, the connection between aging and RNA has remained largely unexplored. Now, a...
