Clinical trial tests herpes virus-based therapy for neurogenic bladder in people with spinal cord...
A modified herpes virus that targets spinal cord nerve cells to treat neurogenic bladder in people with spinal cord injury is underway in a first-in-human clinical trial by UTHealth Houston at TIRR Memorial Hermann. Neurogenic bladder, also called...
Extrachromosomal DNA Carrying MYC Drives Pancreatic Cancer Aggression
Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%. The poor prognosis is due in part both to late detection and the cancer’s capacity to adapt and...
Novel Antibody Targets Tumor Growth in Treatment-Resistant Breast and Ovarian Cancers
Immunotherapy has gained momentum as a pivotal alternative treatment for cancer, revolutionizing the way oncologists approach malignant diseases. By harnessing the body’s immune system, specifically through antibody treatment, this innovative strategy focuses on defending...
Researchers Predict Seismic Damage Risk from Crustal Earthquake Scenarios in Mexico City
A swarm of minor seismic activity has recently caught the attention of researchers examining the tectonic dynamics of Mexico City. Earthquakes with magnitudes ranging from 3 to 5 have been recorded in close succession...
Introducing SSA: A Novel Approach for Semantic Structure-Aware Inference in Weakly Supervised Pixel-Wise Dense...
A groundbreaking research endeavor presented by Yanpeng Sun and Zechao Li has unveiled significant advancements in the realm of computer vision, particularly focusing on the implementation and optimization of Class Activation Mapping (CAM). CAM...
Sex Hormone Protects Against Opioid Misuse in Female Rats
Most people who misuse opioids take the drugs to relieve pain, but data suggest that men are more likely to misuse and overdose on opioids than women, even though they suffer less chronic pain....
Many individuals with Niemann-Pick disease lack neutralizing antibodies against AAV2 or AAV9
A new study in the peer-reviewed journal Human Gene Therapy showed that more than half of individuals with Niemann-Pick disease, type C1 (NPC1) who were tested lacked neutralizing antibodies against either adeno-associated virus (AAV) 2 or...
siRNAs May Provide New Approach to Fight Antibiotic-Resistant Bacterial Infections
Given the growing antibiotic resistance crisis, novel ways to target bacterial infections are becoming increasingly important. One potential strategy is to manipulate bacterial genes at the transcriptional level by silencing their resistance genes. However,...
Megalodon’s Size and Shape Reveal Insights into Aquatic Vertebrate Gigantism
CHICAGO — A recent groundbreaking study led by paleobiology professor Kenshu Shimada from DePaul University has shed new light on the biology and morphology of the formidable prehistoric shark, Otodus megalodon. Often sensationalized in...
StockWatch: Trump’s FDA Nominee Eyes Rare Disease-Specific Review Pathways
Martin A. Makary, MD, a surgeon and public policy researcher at Johns Hopkins University, is President Donald Trump’s nominee for commissioner of the FDA. Testifying before the Senate Health, Education, Labor, and Pensions (HELP)...
