Going Gray Too Soon? Scientists Say It Really May Be Due to Stress

Stress has long been anecdotally linked with prematurely graying hair. It’s said, for example, that when Marie Antoinette was captured during the French Revolution, her hair turned white overnight. Anecdote this may be, but...

Roche Buys Ex-U.S. Rights to Sarepta DMD Gene Therapy Candidate SRP-9001 for Up-to-$2.85B+

Roche has acquired exclusive commercial rights outside the United States to Sarepta Therapeutics’ lead gene therapy pipeline candidate SRP-9001 (AAVrh74.MHCK7.micro-dystrophin) for Duchenne muscular dystrophy (DMD), through a licensing agreement that could generate more than...

Nanoscale Gimlet May Give Weakened Antibiotics a Kick

A two-ingredient antibacterial cocktail is more potent than either ingredient alone, even though one of the ingredients is meropenem, an antibiotic that induces multidrug resistance in bacteria. This surprising outcome depends on a twist—or...

Antibody Drug Conjugates: Manufacturing Precision Guided Therapeutics

/* custom css */ .td_uid_1_5dd8dc1e8c755_rand { min-height: 0; } /* custom css */ .td_uid_2_5dd8dc1e8c9d6_rand { vertical-align: baseline; } While the idea of a magic bullet that treats all maladies is a concept grounded in antiquity, antibody...

Intestinal Stretch Tells Brain to Switch Off Appetite

When we say we feel “full” after eating a meal, we probably think that the feeling of satiety results from having a full stomach. The results of studies by researchers at the University of...

Nanoparticles and Cancer Drug Combined to Target Inflammatory Neutrophils

Researchers at Washington State University (WSU) have developed a novel, patent-pending treatment for diseases associated with inflammatory responses, including sepsis, stroke, rheumatoid arthritis, acute lung injury, and atherosclerosis. The new approach, described in Science...

Bioinformatics Tool Tracks Individual Gut Microbial Strain Changes After Antibiotic Use

Researchers at the University of Alabama at Birmingham (UAB) have provided new insights into how antibiotic use in humans can disrupt the communities of bacteria that reside in our gut systems. The team’s studies...

Vaccinating the World One Collaboration at a Time

/* custom css */ .td_uid_1_5dacfc1a80794_rand { min-height: 0; } /* custom css */ .td_uid_2_5dacfc1a80c8e_rand { vertical-align: baseline; } Positive global health outcomes are often contingent on more than just great science, as knowledge sharing is also...

Hyper-Long Telomeres Give Non-Genetically Modified Mice Longer, Healthier Lives

Scientists at the Spanish National Cancer Research Centre (CNIO) generated the first mice that have super-long telomeres in every one of their body cells. Studies with the animals showed that in comparison with mice...

Breathalyzer Sniffs Out Potential Cancer Immunotherapy Responders

A prospective observational trial in patients with advanced non-small cell lung cancer (NSCLC) has found that an electronic nose device that detects chemicals in the breath can identify with 85% accuracy those patients who...