Broadcast Date: November 17, 2020
Time: 8:00 am PT, 11:00 am ET, 17:00 CET
In this GEN webinar, we will learn about UQ’s rapid development of a vaccine candidate for COVID-19.
As part of this inspiring story, we will hear what role Lonza’s GS Xceed® system played in the project. The University of Queensland (UQ) received support from the Coalition of Epidemic Preparedness Innovations (CEPI) in early 2019 as seed funding to establish a rapid response vaccine pipeline based on the “Molecular Clamp”. The Molecular Clamp is a broadly applicable platform technology that facilitates recombinant expression of viral glycoproteins in subunit form without loss of native antigenicity. The molecular clamp efficiently stabilizes soluble viral fusion proteins in their native trimeric ‘pre-fusion’ form. This form is equivalent to that expressed on the virion surface and the principle target for a protective neutralizing antibody response. Since Jan 2020, working alongside CEPI and a team of Australian and International collaborators, the UQ team shifted its Molecular Clamp rapid response program to development of a vaccine candidate for COVID-19. The team moved rapidly through pre-clinical testing and are currently completing early phase clinical studies. The UQ also partnered with CSL, who are currently advancing both large-scale manufacturing and pivotal stage clinical development for widespread distribution and use.
A live Q&A session will follow the presentation, offering you a chance to pose questions to our expert panelist.
Produced with support from:
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