SP-101 gene therapy shows promise for cystic fibrosis treatment

Scientists from Spirovant Sciences describe SP-101, a novel adeno-associated virus (AAV) gene therapy for the treatment of cystic fibrosis (CF) in the peer-reviewed journal Human Gene Therapy. They also showed that after single dose inhaled...

Digital Twins of Biological Systems Inform Drug Development

Unlike the dopplegängers of folklore or the evil twins of popular entertainment, digital twins don’t just appear seemingly out of nowhere. They are painstakingly developed and refined. And neither are they uncanny interlopers or...

StockWatch: Athira Pays Price as Alzheimer’s Candidate Fails Trial

Recent successes in the development of Alzheimer’s disease treatments make it easy to forget sometimes just how difficult it is to drug that disorder and bring new therapies to market. Athira Pharma (ATHA) received a...

Navigating the Regulatory and Manufacturing Realities of mRNA Therapeutic Development

Angela Johnson, PhDSr. Managing Director, Global Regulatory & ComplianceCytiva Katarina StenkloSr. Product ManagerGlobal FlexFactoryCytiva Ola TuvessonChief Technology OfficerNorthX Biologics Linda MathiassonStrategic Customer LeaderCytiva Joe BarberioVice PresidentTechnical OperationsStrand Therapeutics Navigating the Regulatory and Manufacturing Realities...

Artificial Lymphoid Organs Could Help Predict Booster Vaccine Efficacy

Scientists at the Pasteur Institute in France say they have developed artificial lymphoid organ-chips that recreate much of the human immune system’s response to booster vaccines. The technology, described in a study “Modeling memory B...

Harnessing bacteriophages as targeted treatments for drug-resistant bacteria

As antibiotic resistance becomes an increasingly serious threat to our health, the scientific and medical communities are searching for new medicines to fight infections. Researchers at Gladstone Institutes have just moved closer to that...

Making AI Work in Drug Discovery

Sponsored content brought to you by If you’re wondering how to bring AI into your drug discovery lab beyond ChatGPT, you’re not alone. The multitude of solutions and providers creates analysis paralysis, as life sciences...

Insilico Medicine partners with Inimmune to advance immunotherapeutic discovery

Insilico Medicine("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced that the company has achieved a groundbreaking collaboration with Inimmune, which will utilize Chemistry42, Insilico's proprietary generative artificial intelligence (AI) technology to...

Fish gut bacteria may provide new ingredients for skincare

There are some pretty strange ingredients in cosmetics and skin care products. One example is snail mucin -; also known as snail slime -; which is used for its moisturizing and antioxidant properties. But...

Genetic testing: A game-changer for healthcare

As genetic sequencing technology becomes more accessible and efficient, researchers have made significant strides in understanding the genetic underpinnings of various diseases. This knowledge has led to a surge in clinical applications of genetic...