AACR 2024: EpiBiologics Advances Degraders of Membrane-Bound Proteins
SAN DIEGO, CA—For the first time, one-year-old company EpiBiologics is showing proof-of-concept data from their platform for targeted degradation of membrane and extracellular proteins—a treasure trove that has long eluded drug developers.
Ann Lee-Karlon, PhD,...
Coral researchers awarded EXIST start-up funding
Coral farming based on sexual propagation, leading to a more sustainable coral trade and helping to protect coral reefs – this is the goal of SciReef, a new start-up which is emerging from a...
Stopping aspirin one month after coronary stenting procedures significantly reduces bleeding complications in heart...
Withdrawing aspirin one month after percutaneous coronary intervention (PCI) in high-risk heart patients and keeping them on ticagrelor alone safely improves outcomes and reduces major bleeding by more than half when compared to patients...
Inter-atrial shunts may benefit some heart failure patients while harming others
Inter-atrial shunts—investigational devices that create a small pathway for blood to pass from the left to the right side of the heart in order to improve heart failure symptoms and outcomes—may be beneficial to...
New protein-based micromaterials developed for targeted cancer therapy
Researchers at the Universitat Autònoma de Barcelona (UAB), in collaboration with the Sant Pau Research Institute and the CIBER-BBN, have developed micromaterials made up only of proteins, capable of delivering over an extended period...
Bittersweet Symphony: Verve’s Pause on VERVE-101 Narrows LNP-Delivery Strategy
“Believe it or not, there was an explicit strategy to have multiple product candidates to de-risk the delivery issue.”
That is what Verve Therapeutics CEO Sekar Kathiresan, MD, told GEN Edge regarding his conviction that...
How do manufacturing choices affect microfibre shed?
New peer-reviewed research in Frontiers of Environmental Science sheds light on how manufacturing choices influence microfibre release in textiles.
Credit: Source: ‘Investigating the influence of yarn characteristics on microfibre release from knitted fabrics during...
Long-Lived RNA in Nerve Cells Can Last a Lifetime
Contrary to historic understanding of RNA’s longevity in cells, some RNAs can persist in cells throughout the life of an organism. Lead authors, Martin Hetzer, PhD, president of the Institute of Science and Technology...
StockWatch: Investors Less Forgiving than Analysts as Verve Tumbles
Sekar Kathiresan, MD, Verve Therapeutics co-founder and CEO
Investors punished Verve Therapeutics (VERV) this week—but analysts were far more forgiving—after it voluntarily paused an early-stage clinical trial of one of its lead programs, VERVE-101, after...
Pediatric investigation study sheds light on new assessment tool for identifying infants with tongue...
The World Health Organization and several national health organizations recommend exclusive breastfeeding for infants, at least for the first six months of their life to protect the health of infants and mothers. Among breastfeeding...
