Engineered lettuce may turn injectable GLP-1 therapies into oral pills
Few drugs have entered mainstream awareness as quickly or as dramatically as glucagon-like peptide-1, or GLP-1 receptor agonists. Initially approved by the FDA for the treatment of type 2 diabetes, they have since also...
From Discovery to Lot Release: A Validated Suite of Assays for Biologics Drug Development
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Potency assays that fail during tech transfer or comparability studies don’t just delay timelines—they erode regulatory confidence and cost development cycles. Advancing drug candidates and maintaining product quality post-approval...
Machine learning detects early brain changes linked to Alzheimer’s disease
Worcester Polytechnic Institute (WPI) researchers have used a form of artificial intelligence (AI) to analyze anatomical changes in the brain and predict Alzheimer's disease with nearly 93% accuracy. Their research, published in the journal Neuroscience,...
Restoring cellular vibration reduces aggressiveness of advanced vocal cord cancer
The continuous movement of the vocal cords weakens and eventually stops as laryngeal cancer progresses. Researchers have, for the first time, discovered that restoring cellular vibration reduces the aggressiveness of advanced vocal cord cancer....
Stem cells from human primary tooth pulp may help treat chronic-phase cerebral palsy
Cerebral palsy is a condition usually caused by brain damage before or during birth, resulting in impaired posture and movement. Early symptoms are typically subtle, which may delay diagnosis until more obvious signs appear...
UCF researcher explores insulin signaling as new target for diabetic neuropathy
Neuropathy – chronic pain, numbness and tingling in the hands and feet – is a challenging fact of life for many patients with Type 1 diabetes. Thanks to a new National Institutes of Health...
Wisdom Bioscience establishes Scientific Advisory Board to advance oral cancer diagnostics and screening
Wisdom Bioscience, Inc., a biotechnology company pioneering non-invasive oral cancer diagnostics, today announced the formation of its Scientific Advisory Board (SAB) following the close of an initial funding round. The SAB is comprised of...
Omics in Orlando Day 2: A Video Report from AGBT
As the AGBT meeting came to a close, Julianna LeMieux, PhD, Deputy Editor in Chief, chatted with Kevin Davies, PhD, GEN‘s Editorial Director, about some of the biggest news from the meeting. The two...
Neem compound gedunin shows promise against pancreatic cancer
Ramadevi Subramani Reddy, Ph.D., remembers the neem tree from her childhood in India - a plant her grandmother used to treat everything from fevers to infections. Now, in her Texas Tech Health El Paso...
City Therapeutics Pursues ‘Next Generation of RNAi’
About a year after retiring as founding CEO of Alnylam Pharmaceuticals, where he led pioneering efforts to develop drugs based on RNA interference (RNAi), John Maraganore, PhD, came across a paper in PNAS detailing...
