Hydrogel breakthrough offers significant advance in type 1 diabetes treatment
Researchers from the University of Geneva (UNIGE) and Geneva University Hospitals (HUG) have reached a significant advance in the fight against type 1 diabetes. Using an innovative hydrogel that supports insulin-producing cells once transplanted...
New CRISPR breakthrough promises more affordable disease diagnostics
A team of engineers at the University of Florida has developed a new form of CRISPR technology that could make diagnostics and treatments safer, more precise, and more affordable, while opening the door to...
ASGCT 2026: AI-Optimized Cas12l Gene Editor Offers Compact Cas9 Alternative
BOSTON — In a potentially significant advance for the genome editing field, researchers from the biotechnology company Caszyme and the Vilnius University Institute of Biotechnology in Lithuania have developed a potent and compact variant...
ASGCT 2026: Rare Instance of AAV Integration into Human Genome Linked to Brain Tumor
Rebecca Ahrens-Niklas, MD, PhD
BOSTON — A team at Children’s Hospital of Philadelphia (CHOP) led by Rebecca Ahrens-Niklas, MD, PhD, and Lindsey George, MD, has described a case of a brain tumor linked to a...
Implantable Living Materials Contain Infection-Sensing Bacteria That Release Therapeutics
Overcoming a major hurdle in the use of microbes as medicine, researchers at Harvard’s Wyss Institute and John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed an “implantable living materials” (ILMs)...
Qureight to support Mediar Therapeutics’ Phase 2 trial of MTX-474 in diffuse cutaneous Systemic...
Qureight, an end-to-end imaging CRO that provides enterprise-grade imaging and precision endpoints for clinical trials with a focus on lung and heart disease, and Mediar Therapeutics (Mediar), a clinical-stage biotechnology company advancing first-in-class therapies...
Study improves prediction of dangerous outcomed from hypertrophic cardiomyopathy
A sweeping international study has identified ways to detect patients who are at serious risk of sudden death, heart failure or other dangerous outcomes from heart thickening known as hypertrophic cardiomyopathy. The findings will...
New mRNA adjuvant dramatically boosts T-cell vaccine responses in mice
MIT engineers have developed a new way to amplify the T-cell response to mRNA vaccines - an advance that could lead to much more powerful cancer vaccines and stronger protection against infectious diseases. Most...
Visualizing Receptor Transport Within Neurons via Transcytosis
As spindly, elongated cells, neurons must be able to transport proteins and receptors between distant sites in their cell bodies and axons to function properly. A new imaging study by researchers at Johns Hopkins...
Why AI Alone Isn’t Enough for Oligonucleotide Discovery
AI is reshaping drug discovery, and nucleic acid–based medicines, including mRNAs, gene therapy, and oligonucleotide therapeutics, are no exception. By optimizing sequences and chemical modifications for experimental testing, AI accelerates discovery timelines, which is...
