Novartis Commits up to $2.2B Toward Developing Arrowhead siRNA Therapy
Novartis has agreed to license and develop Arrowhead Pharmaceuticals’ preclinical stage small interfering RNA (siRNA) therapy ARO-SNCA, a potential treatment for Parkinson’s disease and other synucleinopathies, plus additional targets, through a collaboration that could...
Exosomes carry key indicators of biological aging
A new research paper featured on the cover of Volume 17, Issue 8 of Aging (Aging-US) was published on July 30, 2025, titled "Exosomes released from senescent cells and circulatory exosomes isolated from human plasma reveal aging-associated proteomic...
Juice up LNP Formulation, Screening, & Analysis with Supercharged Tools
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Thibaut Ben Chimol Assistant Engineer, Sartorius Polyplus View Bio
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Nanostructures boost CRISPR delivery for genetic medicine
With the power to rewrite the genetic code underlying countless diseases, CRISPR holds immense promise to revolutionize medicine. But until scientists can deliver its gene-editing machinery safely and efficiently into relevant cells and...
Aptamer signs therapeutic development agreement with Invizius
Aptamer Group plc, the developer of next-generation synthetic binders for the life sciences industry, is pleased to announce that it has signed a new therapeutic development agreement with Invizius, a clinical-stage biotechnology company focused...
Visualizing lipid transport inside living cells with fluorescence microscopy
To the point: New technique to image single lipids: Lipids are notoriously difficult to detect with light microscopy. Using a new chemical labeling strategy, the Dresden team has overcome this limitation, enabling novel insights...
Clonogenic hepatocytes identified as engines of liver development
In a new study published in the Journal of Hepatology, researchers from the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) show that only 15–20% of hepatocytes in newborn mice - dubbed clonogenic hepatocytes...
UNSW researchers identify key protein that regulates fat storage in cells
UNSW research has shed light on how cells in the body manage and store fat, potentially offering new insights into health. In the study, published in the Proceedings of the National Academy of Sciences,...
VHH Antibodies: Small Size. Big Possibilities.
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This guide shows how single-domain antibodies can unlock crypitic epitopes, streamline CAR-T design, and sepped up the path to multispecific biologics.
Why VHH matters today
Camelid single-domain antibodies pack high affinity and exceptional stability into...
Promising Broad-Spectrum Antiviral Targets Found in Conserved N-glycans
Researchers at the Nanoscience Initiative, Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have made what they describe as a breakthrough in the fight against viral diseases, which could lead to...
